EZH2 in Myeloid Malignancies

Our understanding of the significance of epigenetic dysregulation in the pathogenesis of myeloid malignancies has greatly advanced in the past decade. Enhancer of Zeste Homolog 2 (EZH2) is the catalytic core component of the Polycomb Repressive Complex 2 (PRC2), which is responsible for gene silenci...

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Bibliographic Details
Main Authors: Jenny Rinke, Andrew Chase, Nicholas C. P. Cross, Andreas Hochhaus, Thomas Ernst
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/9/7/1639