External validation of the modified Marsh and Schnider models for medium-chain triglyceride propofol in target-controlled infusion anesthesia

External validation of the modified Marsh and Schnider models for medium-chain triglyceride propofol in target-controlled infusion anesthesia

Abstract Background Propofol formulated with medium- and long-chain triglycerides (MCT/LCT propofol) has rapidly replaced propofol formulated with long-chain triglycerides (LCT propofol). Despite this shift, the modified Marsh and Schnider pharmacokinetic models developed using LCT propofol are stil...

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Bibliographic Details
Main Authors: Seongheon Lee, Dongho Kang, Eunjin Song, Sungah Yoo, Seongwook Jeong
Format: Article
Language:English
Published: BMC 2024-02-01
Series:BMC Anesthesiology
Subjects:
Propofol formulation
Schnider model
Marsh model
Target controlled infusion
External validation
Online Access:https://doi.org/10.1186/s12871-024-02461-5

Internet

https://doi.org/10.1186/s12871-024-02461-5

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