The CHCHD2/Sirt1 corepressors involve in G9a-mediated regulation of RNase H1 expression to control R-loop

R-loops are regulators of many cellular processes and are threats to genome integrity. Therefore, understanding the mechanisms underlying the regulation of R-loops is important. Inspired by the findings on RNase H1-mediated R-loop degradation or accumulation, we focused our interest on the regulatio...

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Bibliographic Details
Main Authors: Le Li, Yequn Wu, Kui Dai, Qing Wang, Shiqi Ye, Qipeng Shi, Zhenfei Chen, Yi-Chun Huang, Weiwei Zhao, Lijia Li
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:Cell Insight
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2772892723000366