Drug Design, In Silico-Profiling of New Pyrrole Derivatives: Promising Anticancer Agents Against Acute Myeloid Leukemia

Drug Design, In Silico-Profiling of New Pyrrole Derivatives: Promising Anticancer Agents Against Acute Myeloid Leukemia

Molecular docking simulation and synthesis of five compounds of N2, N4-bis (2-(4-substituted phenyl)-4-oxothiazolidin-3-yl)-3,5-dimethyl-1H-pyrrole-2,4-dicarboxamide was carried out to evaluate their theoretical binding affinities, targeting acute myeloid leukemia (AML). The chemical structure of t...

Full description

Bibliographic Details
Main Authors: zaid alsalamy, Ayad Kareem Khan, Mohammed Dheyaa Hamdi, Atheer Awad Mehde
Format: Article
Language:English
Published: College of Pharmacy / Mustansiriyah University 2024-07-01
Series:Al-Mustansiriyah Journal of Pharmaceutical Sciences
Subjects:
in silico-profiling
pyrrole derivatives
Schiff bases
thiazolidinones
acute myeloid leukemia
Online Access:https://ajps.uomustansiriyah.edu.iq/index.php/AJPS/article/view/1063

Internet

https://ajps.uomustansiriyah.edu.iq/index.php/AJPS/article/view/1063

Similar Items