SARS-CoV-2 mRNA vaccine induced higher antibody affinity and IgG titers against variants of concern in post-partum vs non-post-partum women

SARS-CoV-2 mRNA vaccine induced higher antibody affinity and IgG titers against variants of concern in post-partum vs non-post-partum women

Summary: Background: Limited knowledge exists in post-partum women regarding durability of SARS-CoV-2 vaccine-induced antibody responses and their neutralising ability against SARS-CoV-2 variants of concern (VOC). Methods: We elucidated longitudinal mRNA vaccination-induced antibody profiles of 13...

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Bibliographic Details
Main Authors: Youri Lee, Gabrielle Grubbs, Sabrina C. Ramelli, Andrea R. Levine, Allison Bathula, Kapil Saharia, Madeleine Purcell, Shreya Singireddy, Colleen L. Dugan, Lindsey Kirchoff, Allison Lankford, Sarah Cipriano, Ryan A. Curto, Jocelyn Wu, Katherine Raja, Emily Kelley, Daniel Herr, Kevin M. Vannella, Supriya Ravichandran, Juanjie Tang, Anthony Harris, Mohammad Sajadi, Daniel S. Chertow, Alison Grazioli, Surender Khurana
Format: Article
Language:English
Published: Elsevier 2022-03-01
Series:EBioMedicine
Subjects:
SARS-CoV-2
COVID-19
Vaccine
Neutralisation
Spike
Affinity maturation
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396422001244

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http://www.sciencedirect.com/science/article/pii/S2352396422001244

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