Transcriptional analysis highlights three distinct immune profiles of high-risk oral epithelial dysplasia

Transcriptional analysis highlights three distinct immune profiles of high-risk oral epithelial dysplasia

Oral potentially malignant disorders (OPMD) are precursors of oral squamous cell carcinoma (OSCC), and the presence of oral epithelial dysplasia (OED) in OPMD confers an increased risk of malignant transformation. Emerging evidence has indicated a role for the immune system in OPMD disease progressi...

Full description

Bibliographic Details
Main Authors: Chai Phei Gan, Bernard Kok Bang Lee, Shin Hin Lau, Thomas George Kallarakkal, Zuraiza Mohamad Zaini, Bryan Kit Weng Lye, Rosnah Binti Zain, Hans Prakash Sathasivam, Joe Poh Sheng Yeong, Natalia Savelyeva, Gareth Thomas, Christian H. Ottensmeier, Hany Ariffin, Sok Ching Cheong, Kue Peng Lim
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Immunology
Subjects:
immune signature
non-immune reactive
immune cytotoxic
oral premalignant lesion
oral epithelial dysplasia
oral potentially malignant disorder
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.954567/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.954567/full

Similar Items