StackPR is a new computational approach for large-scale identification of progesterone receptor antagonists using the stacking strategy

Abstract Progesterone receptors (PRs) are implicated in various cancers since their presence/absence can determine clinical outcomes. The overstimulation of progesterone can facilitate oncogenesis and thus, its modulation through PR inhibition is urgently needed. To address this issue, a novel stack...

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Bibliographic Details
Main Authors: Nalini Schaduangrat, Nuttapat Anuwongcharoen, Mohammad Ali Moni, Pietro Lio’, Phasit Charoenkwan, Watshara Shoombuatong
Format: Article
Language:English
Published: Nature Portfolio 2022-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-20143-5