Daily fluctuations in blood glucose with normal aging are inversely related to hippocampal synaptic mitochondrial proteins

Daily fluctuations in blood glucose with normal aging are inversely related to hippocampal synaptic mitochondrial proteins

Defective brain glucose utilization is a hallmark of Alzheimer’s disease (AD) while Type II diabetes and elevated blood glucose escalate the risk for AD in later life. Isolating contributions of normal aging from coincident metabolic or brain diseases could lead to refined approaches to manage speci...

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Bibliographic Details
Main Authors: Paul W. Braunstein, David J. Horovitz, Andreina M. Hampton, Fiona Hollis, Lori A. Newman, Reilly T. Enos, Joseph A. McQuail
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Aging Brain
Subjects:
Blood glucose
Normal aging
Hippocampus
Oxidative phosphorylation
Glucose transport
Synapse
Online Access:http://www.sciencedirect.com/science/article/pii/S2589958924000124

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http://www.sciencedirect.com/science/article/pii/S2589958924000124

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