Eukaryotic Initiation Factor 2α Kinases Regulate Virulence Functions, Stage Conversion, and the Stress Response in Entamoeba invadens

Eukaryotic Initiation Factor 2α Kinases Regulate Virulence Functions, Stage Conversion, and the Stress Response in Entamoeba invadens

ABSTRACT Entamoeba histolytica is a protozoan parasite that causes amoebic dysentery and liver abscess. This pathogen possesses a two-stage life cycle consisting of an environmentally stable cyst and a pathogenic amoeboid trophozoite. Since infection is acquired by ingestion of cysts from contaminat...

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Bibliographic Details
Main Authors: Heather A. Walters, Brenda H. Welter, Harrison C. Moss, Martha A. Villano, Ronny Orobio-Hurtado, William J. Sullivan, Lesly A. Temesvari
Format: Article
Language:English
Published: American Society for Microbiology 2022-06-01
Series:mSphere
Subjects:
Entamoeba histolytica
dysentery
eIF2 alpha
encystation
host-parasite adhesion
oxidative stress
Online Access:https://journals.asm.org/doi/10.1128/msphere.00131-22

Internet

https://journals.asm.org/doi/10.1128/msphere.00131-22

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