5-ALA in Suspected Low-Grade Gliomas: Current Role, Limitations, and New Approaches

5-ALA in Suspected Low-Grade Gliomas: Current Role, Limitations, and New Approaches

Radiologically suspected low-grade gliomas (LGG) represent a special challenge for the neurosurgeon during surgery due to their histopathological heterogeneity and indefinite tumor margin. Therefore, new techniques are required to overcome these current surgical drawbacks. Intraoperative visualizati...

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Bibliographic Details
Main Authors: Barbara Kiesel, Julia Freund, David Reichert, Lisa Wadiura, Mikael T. Erkkilae, Adelheid Woehrer, Shawn Hervey-Jumper, Mitchel S. Berger, Georg Widhalm
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Oncology
Subjects:
5-ALA
suspected LGG
anaplastic foci
spectroscopic PpIX analysis
fluorescence lifetime imaging
confocal microscopy
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.699301/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.699301/full

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