First-line treatment with TKI plus brain radiotherapy versus TKI alone in EGFR-mutated non-small cell Lung cancer with brain metastases: a systematic review and meta-analysis

Abstract Background It remains uncertain whether first-line treatment with upfront brain radiotherapy (RT) in combined with epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) is superior to EGFR-TKIs alone for EGFR-mutated non-small cell lung cancer with newly diagnosed brain me...

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Bibliographic Details
Main Authors: Yaowen Song, Shuiyu Lin, Jun Chen, Jun Dang
Format: Article
Language:English
Published: BMC 2023-10-01
Series:BMC Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12885-023-11548-0