Synergistic Interactions of a Synthetic Lubricin-Mimetic with Fibronectin for Enhanced Wear Protection

Synergistic Interactions of a Synthetic Lubricin-Mimetic with Fibronectin for Enhanced Wear Protection

Lubricin (LUB), a major mucinous glycoprotein of mammalian synovial fluids, is believed to provide excellent lubrication to cartilage surfaces. Consequently, when joint disease or replacement leads to increased friction and surface damage in the joint, robust synthetic LUB alternatives that could be...

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Bibliographic Details
Main Authors: Roberto C. Andresen Eguiluz, Sierra G. Cook, Mingchee Tan, Cory N. Brown, Noah J. Pacifici, Mihir S. Samak, Lawrence J. Bonassar, David Putnam, Delphine Gourdon
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-06-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
lubricin-mimetic
fibronectin
wear protection
bottlebrush polymer
surface forces apparatus
Online Access:http://journal.frontiersin.org/article/10.3389/fbioe.2017.00036/full

Internet

http://journal.frontiersin.org/article/10.3389/fbioe.2017.00036/full

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