Suppressing Pyroptosis Augments Post-Transplant Survival of Stem Cells and Cardiac Function Following Ischemic Injury

Suppressing Pyroptosis Augments Post-Transplant Survival of Stem Cells and Cardiac Function Following Ischemic Injury

The acute demise of stem cells following transplantation significantly compromises the efficacy of stem cell-based cell therapeutics for infarcted hearts. As the stem cells transplanted into the damaged heart are readily exposed to the hostile environment, it can be assumed that the acute death of t...

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Bibliographic Details
Main Authors: Chang Youn Lee, Seahyoung Lee, Seongtae Jeong, Jiyun Lee, Hyang-Hee Seo, Sunhye Shin, Jun-Hee Park, Byeong-Wook Song, Il-Kwon Kim, Jung-Won Choi, Sang Woo Kim, Gyoonhee Han, Soyeon Lim, Ki-Chul Hwang
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:International Journal of Molecular Sciences
Subjects:
pyroptosis
M1 macrophage
stem cells
miR-762
I/R injury
Online Access:https://www.mdpi.com/1422-0067/22/15/7946

Internet

https://www.mdpi.com/1422-0067/22/15/7946

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