Comprehensive bile acid pool analysis during ex-vivo liver perfusion in a porcine model of ischemia-reperfusion injury

Comprehensive bile acid pool analysis during ex-vivo liver perfusion in a porcine model of ischemia-reperfusion injury

Abstract Bile acids (BA) are key for liver regeneration and injury. This study aims at analyzing the changes in the BA pool induced by ischemia-reperfusion (IRI) and investigates the impact of hypothermic oxygenated perfusion (HOPE) on the BA pool compared to static cold storage (SCS). In a porcine...

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Bibliographic Details
Main Authors: Guillaume Rossignol, Xavier Muller, Thomas Alexandre Brunet, Valeska Bidault, Valerie Hervieu, Yohann Clement, Sophie Ayciriex, Jean-Yves Mabrut, Arnaud Salvador, Kayvan Mohkam
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-52504-7

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https://doi.org/10.1038/s41598-024-52504-7

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