CD3ε Expression Defines Functionally Distinct Subsets of Vδ1 T Cells in Patients With Human Immunodeficiency Virus Infection

CD3ε Expression Defines Functionally Distinct Subsets of Vδ1 T Cells in Patients With Human Immunodeficiency Virus Infection

Human γδ T cells expressing the Vδ1 T cell receptor (TCR) recognize self and microbial antigens and stress-inducible molecules in a major histocompatibility complex-unrestricted manner and are an important source of innate interleukin (IL)-17. Vδ1 T cells are expanded in the circulation and intestin...

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Bibliographic Details
Main Authors: Pádraic J. Dunne, Christina O. Maher, Michael Freeley, Katie Dunne, Andreea Petrasca, Judy Orikiiriza, Margaret R. Dunne, Derval Reidy, Siobhan O’Dea, Aisling Loy, Jim Woo, Aideen Long, Thomas R. Rogers, Fiona Mulcahy, Derek G. Doherty
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Immunology
Subjects:
human immunodeficiency virus
Vδ1 T cells
CD3ε
interleukin-17
programmed death-1
flow cytometry
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00940/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2018.00940/full

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