DHAV 3CD targets IRF7 and RIG-I proteins to block the type I interferon upstream signaling pathway

DHAV 3CD targets IRF7 and RIG-I proteins to block the type I interferon upstream signaling pathway

Abstract Duck hepatitis A virus type 1 (DHAV-1) is an acute, highly lethal infectious agent that infects ducklings and causes up to 95% mortality in ducklings up to 1 week of age, posing a significant economic threat to the duck farming industry. Previous studies have found that the proteolytic enzy...

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Bibliographic Details
Main Authors: Xiaoyan Xia, Anchun Cheng, Mingshu Wang, Xumin Ou, Di Sun, Shaqiu Zhang, Sai Mao, Qiao Yang, Bin Tian, Ying Wu, Juan Huang, Qun Gao, Renyong Jia, Shun Chen, Mafeng Liu, Xin-Xin Zhao, Dekang Zhu, Yanling Yu, Ling Zhang
Format: Article
Language:English
Published: BMC 2023-01-01
Series:Veterinary Research
Subjects:
Duck hepatitis a virus
3CD protein
interferon regulatory factor 7
retinoic acid-inducible gene I
interaction
immune evasion
Online Access:https://doi.org/10.1186/s13567-023-01134-4

Internet

https://doi.org/10.1186/s13567-023-01134-4

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