Computational model of membrane fission catalyzed by ESCRT-III.

ESCRT-III proteins catalyze membrane fission during multi vesicular body biogenesis, budding of some enveloped viruses and cell division. We suggest and analyze a novel mechanism of membrane fission by the mammalian ESCRT-III subunits CHMP2 and CHMP3. We propose that the CHMP2-CHMP3 complexes self-a...

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Bibliographic Details
Main Authors: Gur Fabrikant, Suman Lata, James D Riches, John A G Briggs, Winfried Weissenhorn, Michael M Kozlov
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-11-01
Series:PLoS Computational Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19936052/?tool=EBI