Deletion of histone deacetylase 7 in osteoclasts decreases bone mass in mice by interactions with MITF.

Deletion of histone deacetylase 7 in osteoclasts decreases bone mass in mice by interactions with MITF.

Molecular regulators of osteoclast formation and function are an important area of research due to the central role of osteoclasts in bone resorption. Transcription factors such as MITF are essential for osteoclast generation by regulating expression of the genes required for cellular differentiatio...

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Bibliographic Details
Main Authors: Melissa Stemig, Kristina Astelford, Ann Emery, Jangyeun J Cho, Ben Allen, Tsang-hai Huang, Rajaram Gopalakrishnan, Kim C Mansky, Eric D Jensen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4398560?pdf=render

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http://europepmc.org/articles/PMC4398560?pdf=render

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