<i>Aggregatibacter actinomycetemcomitans</i> Leukotoxin Activates the NLRP3 Inflammasome and Cell-to-Cell Communication
Carriers of highly leukotoxic genotypes of <i>Aggregatibacter actinomycetemcomitans</i> are at high risk for rapid degradation of tooth-supporting tissues. The leukotoxin (LtxA) expressed by this bacterium induces a rapid pro-inflammatory response in leukocytes that results in cell death...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-01-01
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| Series: | Pathogens |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-0817/11/2/159 |