Sex differences of molecular mechanisms of insulin sensitivity in young and adult C57BL/6J mice

Sex differences of molecular mechanisms of insulin sensitivity in young and adult C57BL/6J mice

Reduced insulin sensitivity plays an important role in the pathogenesis of type II diabetes. There are sex differences in the development of metabolic disorders. The aim of this work was to investigate the insulin signal transduction gene expression in mice of different sex and age. Male and female...

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Bibliographic Details
Main Authors: T. V. Yakovleva, A. Yu. Kazantseva, E. N.  Makarova, N. M. Bazhan
Format: Article
Language:English
Published: Siberian Branch of the Russian Academy of Sciences, Federal Research Center Institute of Cytology and Genetics, The Vavilov Society of Geneticists and Breeders 2017-12-01
Series:Вавиловский журнал генетики и селекции
Subjects:
sex differences
glucose tolerance
insulin sensitivity
mrna
insr
irs1/2
pik3cd
slc2a2/4
real-time pcr, mouse c57bl/6j
Online Access:https://vavilov.elpub.ru/jour/article/view/1233

Internet

https://vavilov.elpub.ru/jour/article/view/1233

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