Asymmetric Synthesis and Antimicrobial Activity of Some New Mono and Bicyclic β-Lactams
Reaction of the amino acid D-phenylalanine ethyl ester (4) with cinnamaldehyde gave chiral Schiff base 5, which underwent an asymmetric Staudinger [2+2] cycloaddition reaction with phthalimidoacetyl chloride to give the monocyclic β-lactam 6 as a single stereoisomer. Ozonolysis of 6 followed by r...
| Váldodahkkit: | , , |
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| Materiálatiipa: | Artihkal |
| Giella: | English |
| Almmustuhtton: |
MDPI AG
2004-11-01
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| Ráidu: | Molecules |
| Fáttát: | |
| Liŋkkat: | http://www.mdpi.com/1420-3049/9/11/939/ |