Angiotensin converting enzyme 2 does not facilitate porcine epidemic diarrhea virus entry into porcine intestinal epithelial cells and inhibits it-induced inflammatory injury by promoting STAT1 phosphorylation

Angiotensin converting enzyme 2 does not facilitate porcine epidemic diarrhea virus entry into porcine intestinal epithelial cells and inhibits it-induced inflammatory injury by promoting STAT1 phosphorylation

ACE2 has been confirmed to be a functional receptor for SARS-CoV and SARS-CoV-2, but research on animal coronaviruses, especially PEDV, are still unknown. The present study investigated whether ACE2 plays a role in receptor recognition and subsequent infection during PEDV invasion of host cells. IPE...

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Bibliographic Details
Main Authors: Zhiqiang Li, Xueqing Chen, Chang Ma, Xinyu Du, Yuanshu Zhang
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Virus Research
Subjects:
ACE2
PEDV
N protein
IPEC-J2
STAT1
Inflammatory injury
Online Access:http://www.sciencedirect.com/science/article/pii/S0168170223002629

Internet

http://www.sciencedirect.com/science/article/pii/S0168170223002629

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