Stress stimulation maintaining by genipin crosslinked hydrogel promotes annulus fibrosus healing

Objective: To explore the repair effect of tissue engineering for annulus fibrosus (AF) injury in stress-stimulation environment. Methods: Non-adhesive fibrinogen (Fib) representing the repair with non-stress stimulation and adhesive hydrogel of fibrinogen, thrombin and genipin mixture (Fib-T-G) rep...

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Bibliographic Details
Main Authors: Zihan Wang, Xiaoyu Jin, Botao Zhang, Jiaxin Kong, Rongrong Deng, Ke Wu, Lin Xie, Xin Liu, Ran Kang
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:Journal of Orthopaedic Translation
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2214031X23000372