Stress stimulation maintaining by genipin crosslinked hydrogel promotes annulus fibrosus healing

Stress stimulation maintaining by genipin crosslinked hydrogel promotes annulus fibrosus healing

Objective: To explore the repair effect of tissue engineering for annulus fibrosus (AF) injury in stress-stimulation environment. Methods: Non-adhesive fibrinogen (Fib) representing the repair with non-stress stimulation and adhesive hydrogel of fibrinogen, thrombin and genipin mixture (Fib-T-G) rep...

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Bibliographic Details
Main Authors:	Zihan Wang, Xiaoyu Jin, Botao Zhang, Jiaxin Kong, Rongrong Deng, Ke Wu, Lin Xie, Xin Liu, Ran Kang
Format:	Article
Language:	English
Published:	Elsevier 2023-05-01
Series:	Journal of Orthopaedic Translation
Subjects:	Stress stimulation Annulus fibrosus Genipin crosslinking Hydrogel Mesenchymal stromal cells (MSCs) RhoA/ROCK
Online Access:	http://www.sciencedirect.com/science/article/pii/S2214031X23000372

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