Crystal structure of the CoV-Y domain of SARS-CoV-2 nonstructural protein 3

Abstract Replication of the coronavirus genome starts with the formation of viral RNA-containing double-membrane vesicles (DMV) following viral entry into the host cell. The multi-domain nonstructural protein 3 (nsp3) is the largest protein encoded by the known coronavirus genome and serves as a cen...

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Bibliographic Details
Main Authors: Yunfeng Li, Yulia Pustovalova, Wuxian Shi, Oksana Gorbatyuk, Sridhar Sreeramulu, Harald Schwalbe, Jeffrey C. Hoch, Bing Hao
Format: Article
Language:English
Published: Nature Portfolio 2023-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-30045-9