Immunogenicity and Safety of Homologous and Heterologous Prime–Boost Immunization with COVID-19 Vaccine: Systematic Review and Meta-Analysis

A prime–boost strategy of COVID-19 vaccines brings hope to limit the spread of SARS-CoV-2, while the immunogenicity of the vaccines is waning over time. Whether a booster dose of vaccine is needed has become a widely controversial issue. However, no published meta-analysis has focused on the issue....

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Bibliographic Details
Main Authors: Haoyue Cheng, Zhicheng Peng, Shuting Si, Xialidan Alifu, Haibo Zhou, Peihan Chi, Yan Zhuang, Minjia Mo, Yunxian Yu
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Vaccines
Subjects:
Online Access:https://www.mdpi.com/2076-393X/10/5/798