The Association of <i>HLA-B*35</i> and <i>GSTT1</i> Genotypes and Hepatotoxicity in Thai People Living with HIV

The Association of <i>HLA-B*35</i> and <i>GSTT1</i> Genotypes and Hepatotoxicity in Thai People Living with HIV

Glutathione s-transferase (GST) is a family of drug-metabolizing enzymes responsible for metabolizing and detoxifying drugs and xenobiotic substances. Therefore, deletion polymorphisms of <i>GST</i>s can be implicated in developing several pathological conditions, including antiretrovira...

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Bibliographic Details
Main Authors: Noppadol Chanhom, Jiraphun Jittikoon, Sukanya Wattanapokayakit, Surakameth Mahasirimongkol, Angkana Charoenyingwattana, Wanvisa Udomsinprasert, Usa Chaikledkaew, Supharat Suvichapanich, Taisei Mushiroda, Sasisopin Kiertiburanakul, Archawin Rojanawiwat, Wittaya Wangsomboonsiri, Weerawat Manosuthi, Pacharee Kantipong, Anucha Apisarnthanarak, Wilawan Sangsirinakakul, Pawinee Wongprasit, Romanee Chaiwarith, Woraphot Tantisiriwat, Somnuek Sungkanuparph, Wasun Chantratita
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Journal of Personalized Medicine
Subjects:
drug-induced liver injury
glutathione s-transferase
human immunodeficiency virus
hepatotoxicity
adverse drug reaction
genetic polymorphisms
Online Access:https://www.mdpi.com/2075-4426/12/6/940

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https://www.mdpi.com/2075-4426/12/6/940

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