Synthesis of Tricyclic Pterolobirin H Analogue: Evaluation of Anticancer and Anti-Inflammatory Activities and Molecular Docking Investigations

Synthesis of Tricyclic Pterolobirin H Analogue: Evaluation of Anticancer and Anti-Inflammatory Activities and Molecular Docking Investigations

Pterolobirin H (<b>3</b>), a cassane diterpene isolated from the roots of Pterolobium macropterum, exhibits important anti-inflammatory and anticancer properties. However, its relatively complex tetracyclic structure makes it difficult to obtain by chemical synthesis, thus limiting the s...

Full description

Bibliographic Details
Main Authors: Houda Zentar, Fatin Jannus, Marta Medina-O’Donnell, Az-eddine El Mansouri, Antonio Fernández, José Justicia, Enrique Alvarez-Manzaneda, Fernando J. Reyes-Zurita, Rachid Chahboun
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Molecules
Subjects:
function-oriented synthesis (FOS)
cassane diterpenoids
anticancer
anti-inflammatory
docking
Online Access:https://www.mdpi.com/1420-3049/28/17/6208

Internet

https://www.mdpi.com/1420-3049/28/17/6208

Similar Items