Orphan nuclear receptor NR4A2 inhibits hepatic stellate cell proliferation through MAPK pathway in liver fibrosis

Hepatic stellate cells (HSCs) play a crucial role in liver fibrosis, which is a pathological process characterized by extracellular matrix accumulation. NR4A2 is a nuclear receptor belonging to the NR4A subfamily and vital in regulating cell growth, metabolism, inflammation and other biological func...

Full description

Bibliographic Details
Main Authors: Pengguo Chen, Jie Li, Yan Huo, Jin Lu, Lili Wan, Bin Li, Run Gan, Cheng Guo
Format: Article
Language:English
Published: PeerJ Inc. 2015-12-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/1518.pdf