Armillariella tabescens methanol extract ameliorates ulcerative colitis via inhibiting TLR4/NF-κB and NLRP3 activation and mediating intestinal barrier integrity

Armillariella tabescens methanol extract ameliorates ulcerative colitis via inhibiting TLR4/NF-κB and NLRP3 activation and mediating intestinal barrier integrity

Armillariella tabescens is a traditional Chinese medicinal and edible fungus which holds importance for treatment of gastrointestinal disorders. This study was aimed to evaluate the effect of methanol extract of A. tabescens (AME) in dextran sulfate sodium (DSS) induced ulcerative colitis (UC). The...

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Bibliographic Details
Main Authors: Wen-Na Zhang, Yuan-Yuan Li, Jia-Jia Xu, Lu-Lu Shi, Lei Chen, Yong-Ming Lu, Qing-Xi Wu, Jian-Guang Luo, Yan Chen
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Journal of Functional Foods
Subjects:
Armillariella tabescens
Ulcerative colitis
Tight junction proteins
TLR4/NF-κB
NLRP3
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464622003711

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http://www.sciencedirect.com/science/article/pii/S1756464622003711

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