Aspiletrein A Induces Apoptosis Cell Death via Increasing Reactive Oxygen Species Generation and AMPK Activation in Non-Small-Cell Lung Cancer Cells

Aspiletrein A Induces Apoptosis Cell Death via Increasing Reactive Oxygen Species Generation and AMPK Activation in Non-Small-Cell Lung Cancer Cells

Lung cancer remains a leading cause of death in cancer patients, and deregulation of apoptosis is a serious concern in clinical practice, even though therapeutic intervention has been greatly improved. Plants are a versatile source of biologically active compounds for anticancer drug discovery, and...

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Bibliographic Details
Main Authors: Wasita Witayateeraporn, Hien Minh Nguyen, Duc Viet Ho, Hoai Thi Nguyen, Pithi Chanvorachote, Chanida Vinayanuwattikun, Varisa Pongrakhananon
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:International Journal of Molecular Sciences
Subjects:
aspiletrein A
AMP-activated protein kinase
apoptosis
non-small-cell lung cancer cells
reactive oxygen species
Online Access:https://www.mdpi.com/1422-0067/23/16/9258

Internet

https://www.mdpi.com/1422-0067/23/16/9258

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