Improved Prostate-Specific Membrane Antigen (PSMA) Stimulation Using a Super Additive Effect of Dutasteride and Lovastatin In Vitro

Improved Prostate-Specific Membrane Antigen (PSMA) Stimulation Using a Super Additive Effect of Dutasteride and Lovastatin In Vitro

Prostate-specific membrane antigen (PSMA)-based imaging improved the detection of primary, recurrent and metastatic prostate cancer. However, in certain patients, a low PSMA surface expression can be a limitation for this promising diagnostic tool. Pharmacological induction of PSMA might be useful t...

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Bibliographic Details
Main Authors: Aleksandar Kuzmanov, Souzan Salemi, Florian A. Schmid, Irene A. Burger, Daniel Eberli, Benedikt Kranzbühler
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:International Journal of Molecular Sciences
Subjects:
prostate-specific membrane antigen (PSMA)
androgen receptor (AR)
dutasteride (Duta)
lovastatin (Lova)
dutasteride + lovastatin (Duta + Lova) treatment
Online Access:https://www.mdpi.com/1422-0067/24/15/12338

Internet

https://www.mdpi.com/1422-0067/24/15/12338

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