A New Method to Develop the Primate Model of Knee Osteoarthritis With Focal Cartilage Defect

Objective: Osteoarthritis (OA) is a common degenerative joint disease, and animal models have proven pivotal in investigating this disease. This study aimed to develop a primate model of OA that may be more relevant to research studies on OA in humans.Method: Twelve female rhesus macaques were rando...

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Bibliographic Details
Main Authors: Xin Bi, Tao Li, Min Li, Shutian Xiang, Junhong Li, Bin Ling, Zhaoxiang Wu, Zhong Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2021.727643/full