Deletions of neuraminidase and resistance to oseltamivir may be a consequence of restricted receptor specificity in recent H3N2 influenza viruses

<p>Abstract</p> <p>Background</p> <p>Influenza viruses attach to cells via sialic acid receptors. The viral neuraminidase (NA) is needed to remove sialic acids so that newly budded virions can disperse. Known mechanisms of resistance to NA inhibitors include mutations i...

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Bibliographic Details
Main Authors: Air Gillian M, Smith David F, Gulati Shelly
Format: Article
Language:English
Published: BMC 2009-02-01
Series:Virology Journal
Online Access:http://www.virologyj.com/content/6/1/22