A mass spectrometry imaging and lipidomic investigation reveals aberrant lipid metabolism in the orthotopic mouse glioma

A mass spectrometry imaging and lipidomic investigation reveals aberrant lipid metabolism in the orthotopic mouse glioma

Lipids perform multiple biological functions and reflect the physiology and pathology of cells, tissues, and organs. Here, we sought to understand lipid content in relation to tumor pathology by characterizing phospholipids and sphingolipids in the orthotopic mouse glioma using MALDI MS imaging (MSI...

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Bibliographic Details
Main Authors: Hay-Yan J. Wang, Chiung-Yin Huang, Kuo-Chen Wei, Kuo-Chen Hung
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Journal of Lipid Research
Subjects:
tumor pathology
phospholipids
sphingolipids
MALDI MS imaging
unsupervised clustering analysis
LC-MS/MS
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227522001377

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http://www.sciencedirect.com/science/article/pii/S0022227522001377

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