Comparing the Impact of Atropine Drops and Amitriptyline Tablets in Treatment of Clozapine-Induced Sialorrhea: A Randomized Double-Blind Placebo Controlled Clinical Trial

Clozapine is an atypical antipsychotic employed to treat patients with psychotic disorders. It is associated with sialorrhea as a problematic adverse effect in 30-80% of cases. Various medications such as atropine and amitriptyline have been suggested for its treatment. We aimed to compare the effec...

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Bibliographic Details
Main Authors: Fatemeh Sheikhmoonesi, Mehran Zarghami, Narjes Hendoie, Paria Azari, Jamshid Yazdani Cherati, Maryam Rezapour
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2019-01-01
Series:Acta Medica Iranica
Subjects:
Online Access:https://acta.tums.ac.ir/index.php/acta/article/view/6930