Assessing Anti-HCMV Cell Mediated Immune Responses in Transplant Recipients and Healthy Controls Using a Novel Functional Assay

Assessing Anti-HCMV Cell Mediated Immune Responses in Transplant Recipients and Healthy Controls Using a Novel Functional Assay

HCMV infection, reinfection or reactivation occurs in 60% of untreated solid organ transplant (SOT) recipients. Current clinical approaches to HCMV management include pre-emptive and prophylactic antiviral treatment strategies. The introduction of immune monitoring to better stratify patients at ris...

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Bibliographic Details
Main Authors: Charlotte J. Houldcroft, Sarah E. Jackson, Eleanor Y. Lim, George X. Sedikides, Emma L. Davies, Claire Atkinson, Megan McIntosh, Ester B. M. Remmerswaal, Georgina Okecha, Frederike J. Bemelman, Richard J. Stanton, Matthew Reeves, Mark R. Wills
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
herpesvirus
host-pathogen interactions
secreted immunity
T cells
transplantation
cell-mediated immunity
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2020.00275/full

Internet

https://www.frontiersin.org/article/10.3389/fcimb.2020.00275/full

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