Acanthamoeba and Dictyostelium as Cellular Models for Legionella Infection

Acanthamoeba and Dictyostelium as Cellular Models for Legionella Infection

Environmental bacteria of the genus Legionella naturally parasitize free-living amoebae. Upon inhalation of bacteria-laden aerosols, the opportunistic pathogens grow intracellularly in alveolar macrophages and can cause a life-threatening pneumonia termed Legionnaires' disease. Intracellular re...

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Bibliographic Details
Main Authors: A. Leoni Swart, Christopher F. Harrison, Ludwig Eichinger, Michael Steinert, Hubert Hilbi
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-03-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
amoebae
effector protein
GTPase
host-pathogen interaction
pathogen vacuole
phosphoinositide lipid
Online Access:http://journal.frontiersin.org/article/10.3389/fcimb.2018.00061/full

Internet

http://journal.frontiersin.org/article/10.3389/fcimb.2018.00061/full

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