Influence of G-protein β-Polypeptide 3 C825T Polymorphism on Antihypertensive Response to Telmisartan and Amlodipine in Chinese Patients

Influence of G-protein β-Polypeptide 3 C825T Polymorphism on Antihypertensive Response to Telmisartan and Amlodipine in Chinese Patients

Background: G-protein β-polypeptide 3 (GNB3) is a β subunit isoform of G-protein that plays important role in signal transduction of membrane G-protein coupled receptors (GPCRs). The GNB3 splice variant C825T (rs5443) is associated with risk for essential hypertension (EH) and efficacy of therapeuti...

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Bibliographic Details
Main Authors: Zan-Lin Zhang, Hui-Lan Li, Zhi-Peng Wen, Guo-Ping Yang, Wei Zhang, Xiao-Ping Chen
Format: Article
Language:English
Published: Wolters Kluwer 2016-01-01
Series:Chinese Medical Journal
Subjects:
Amlodipine; Chinese Population; G-protein β-polypeptide 3; Single Nucleotide Polymorphism; Telmisartan
Online Access:http://www.cmj.org/article.asp?issn=0366-6999;year=2016;volume=129;issue=1;spage=8;epage=14;aulast=Zhang

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http://www.cmj.org/article.asp?issn=0366-6999;year=2016;volume=129;issue=1;spage=8;epage=14;aulast=Zhang

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