Gram-negative bacteria and their lipopolysaccharides in Alzheimer’s disease: pathologic roles and therapeutic implications

Gram-negative bacteria and their lipopolysaccharides in Alzheimer’s disease: pathologic roles and therapeutic implications

Abstract Alzheimer’s disease (AD) is the most serious age-related neurodegenerative disease and causes destructive and irreversible cognitive decline. Failures in the development of therapeutics targeting amyloid-β (Aβ) and tau, principal proteins inducing pathology in AD, suggest a paradigm shift t...

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Bibliographic Details
Main Authors: Hyeon soo Kim, Sujin Kim, Soo Jung Shin, Yong Ho Park, Yunkwon Nam, Chae won Kim, Kang won Lee, Sung-Min Kim, In Duk Jung, Hyun Duk Yang, Yeong-Min Park, Minho Moon
Format: Article
Language:English
Published: BMC 2021-12-01
Series:Translational Neurodegeneration
Subjects:
Alzheimer’s disease
Gram-negative bacteria
Lipopolysaccharide
Exotoxin
Amyloid beta
Tau
Online Access:https://doi.org/10.1186/s40035-021-00273-y

Internet

https://doi.org/10.1186/s40035-021-00273-y

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