Smoking‐Induced M2‐TAMs, via circEML4 in EVs, Promote the Progression of NSCLC through ALKBH5‐Regulated m6A Modification of SOCS2 in NSCLC Cells

Smoking‐Induced M2‐TAMs, via circEML4 in EVs, Promote the Progression of NSCLC through ALKBH5‐Regulated m6A Modification of SOCS2 in NSCLC Cells

Abstract Lung cancer is a commonly diagnosed disease worldwide, with non‐small cell lung cancers (NSCLCs) accounting for ≈ 85% of cases. Cigarette smoke is an environmental exposure promoting progression of NSCLC, but its role is poorly understood. This study reports that smoking‐induced accumulatio...

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Bibliographic Details
Main Authors: Cheng Cheng, Peiwen Wang, Yi Yang, Xuan Du, Haibo Xia, Jinyuan Liu, Lu Lu, Hao Wu, Qizhan Liu
Format: Article
Language:English
Published: Wiley 2023-08-01
Series:Advanced Science
Subjects:
circRNAs
N6‐methyladenosine
non‐small cell lung cancer
smoking
tumor‐associated macrophages
Online Access:https://doi.org/10.1002/advs.202300953

Internet

https://doi.org/10.1002/advs.202300953

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