Consistent and correctable bias in metagenomic sequencing experiments

Marker-gene and metagenomic sequencing have profoundly expanded our ability to measure biological communities. But the measurements they provide differ from the truth, often dramatically, because these experiments are biased toward detecting some taxa over others. This experimental bias makes the ta...

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Bibliographic Details
Main Authors: Michael R McLaren, Amy D Willis, Benjamin J Callahan
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-09-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/46923