WNT7A Promotes EGF-Induced Migration of Oral Squamous Cell Carcinoma Cells by Activating β-Catenin/MMP9-Mediated Signaling

WNT7A Promotes EGF-Induced Migration of Oral Squamous Cell Carcinoma Cells by Activating β-Catenin/MMP9-Mediated Signaling

Aims and hypothesisEpidermal growth factor (EGF) has been shown to induce the migration of various cancer cells. However, the underlying signaling mechanisms for EGF-induced migration of oral squamous cell carcinoma (OSCC) remain to be elucidated. WNT7A, a member of the family of 19 Wnt secreted gly...

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Bibliographic Details
Main Authors: Hui Xie, Yadong Ma, Jun Li, Huixia Chen, Yongfu Xie, Minzhen Chen, Xuyang Zhao, Sijie Tang, Shuo Zhao, Yujie Zhang, Jun Du, Feimin Zhang, Luo Gu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Pharmacology
Subjects:
EGF
WNT7A
AKT
migration
OSCC
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00098/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2020.00098/full

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