A complex of cadherin 17 with desmocollin 1 and p120-catenin regulates colorectal cancer migration and invasion according to the cell phenotype
Abstract Background Cadherin-17 (CDH17), a marker of differentiation in intestinal cells, binds and activates α2β1 integrin to promote cell adhesion and proliferation in colorectal cancer (CRC) metastasis. Furthermore, CDH17 associates with p120- and β-catenin in a manner yet to be fully elucidated....
| Main Authors: | , , , , , , , , , |
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| פורמט: | Article |
| שפה: | English |
| יצא לאור: |
BMC
2024-01-01
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| סדרה: | Journal of Experimental & Clinical Cancer Research |
| נושאים: | |
| גישה מקוונת: | https://doi.org/10.1186/s13046-024-02956-6 |