Rapid stability-indicating UHPLC method for determination of lamivudine and tenofovir disoproxil fumarate in fixed-dose combination tablets

Lamivudine (3TC) and tenofovir disoproxil fumarate (TDF) are antiretroviral drugs widely used for AIDS treatment. Since safety, efficacy and quality are essential for drug products, stability studies must be performed. Therefore, degradation studies must be carried out to evaluate the degradation pr...

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Bibliographic Details
Main Authors: Danielle Evangelista Rabelo de Souza, Nicoly Kaliny Magela Gomes, Gerson Antônio Pianetti, Bruno Gonçalves Pereira, Christian Fernandes
Format: Article
Language:English
Published: Universidade Federal do Rio Grande do Sul 2021-12-01
Series:Drug Analytical Research
Online Access:https://seer.ufrgs.br/index.php/produto&producao/ojs/include/index.php/dar/article/view/117905