De Novo Glycine Synthesis Is Reduced in Adults With Morbid Obesity and Increases Following Bariatric Surgery

De Novo Glycine Synthesis Is Reduced in Adults With Morbid Obesity and Increases Following Bariatric Surgery

BackgroundGlycine is a dietary non-essential amino acid that is low in obesity and increases following bariatric surgery. However, the exact mechanism responsible remains unclear and it is unknown whether hypoglycinemia is a cause or consequence of insulin resistance.ObjectiveUsing multiple isotopic...

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Bibliographic Details
Main Authors: Hong Chang Tan, Jean W. Hsu, E Shyong Tai, Shaji Chacko, Vieon Wu, Chun Fan Lee, Jean-Paul Kovalik, Farook Jahoor
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Endocrinology
Subjects:
morbid obesity
bariatric surgery
de novo glycine synthesis
insulin resistancE
stable-isotope tracers
metabolic flux
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.900343/full

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https://www.frontiersin.org/articles/10.3389/fendo.2022.900343/full

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