Inferring cell-type-specific causal gene regulatory networks during human neurogenesis
Abstract Background Genetic variation influences both chromatin accessibility, assessed in chromatin accessibility quantitative trait loci (caQTL) studies, and gene expression, assessed in expression QTL (eQTL) studies. Genetic variants can impact either nearby genes (cis-eQTLs) or distal genes (tra...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-05-01
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Series: | Genome Biology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13059-023-02959-0 |