Support for the Transmission-Clearance Trade-Off Hypothesis from a Study of Zika Virus Delivered by Mosquito Bite to Mice

Evolutionary theory indicates that virus virulence is shaped by a trade-off between instantaneous rate of transmission and duration of infection. For most viruses, infection is curtailed by immune clearance, but there are few empirical tests of the transmission−clearance trade-off hypothes...

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Bibliographic Details
Main Authors: Kathryn A. Hanley, Sasha R. Azar, Rafael K. Campos, Nikos Vasilakis, Shannan L. Rossi
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/11/11/1072