Polymorphism in interferon alpha/beta receptor contributes to glucocorticoid response and outcome of ARDS and COVID-19

Abstract Background The use of glucocorticoids has given contradictory results for treating acute respiratory distress syndrome (ARDS). The use of intravenous Interferon beta (IFN β) for the treatment of ARDS was recently tested in a phase III ARDS trial (INTEREST), in which more than half of the pa...

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Bibliographic Details
Main Authors: Juho Jalkanen, Sofia Khan, Kati Elima, Teppo Huttunen, Ning Wang, Maija Hollmén, Laura L. Elo, Sirpa Jalkanen
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Critical Care
Subjects:
Online Access:https://doi.org/10.1186/s13054-023-04388-8