Combining network modeling and gene expression microarray analysis to explore the dynamics of Th1 and Th2 cell regulation.
Two T helper (Th) cell subsets, namely Th1 and Th2 cells, play an important role in inflammatory diseases. The two subsets are thought to counter-regulate each other, and alterations in their balance result in different diseases. This paradigm has been challenged by recent clinical and experimental...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2010-01-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC3002992?pdf=render |